WSU to Study Iraq Toxins' Effect

Spokesman-Review
by Bert Caldwell


Research to examine how exposure might damage offspring of soldiers

Washington State University scientists will use a $1.7 million grant to study what multi-generation genetic damage might be done by toxins U.S. troops could encounter in Iraq.

The research using laboratory rats, not humans, will be the first for the military to examine the epigenetic effects of pesticides, herbicides and other compounds, said lead scientist Michael Skinner, director of the university's Center for Reproductive Biology.

Previous studies have looked at the health effects of other substances, notably the Agent Orange used to defoliate jungles in Vietnam, on the soldiers directly exposed, he said, not on their children or grandchildren.

"The science really had not caught up with the trans-generational stuff," said Skinner, one of several WSU pioneers in the field of epigenetic, or multi-generational, inheritance.

Besides herbicides and pesticides – which and in what combinations has not been determined – the study also will look at the effects of explosives residues, he said.

The four-year study will allow researchers to see how any changes in genetic chemistry that develop are passed along through two subsequent generations of rats, he said, noting that only the first two years of research have been funded.

Among the problems that might develop are kidney disease, or changes in the male and female reproductive organs, he said.

If any genetic markers are identified in rats, Skinner said, follow-up research could look at whether they might show up among members of the military as well.

That would be of particular interest to Dave Holmes, interim chief operating officer of the Institute for Systems Medicine, which was awarded the U.S. Department of Defense grant passed through to Skinner.

Holmes' son, Tim Hammond, did two tours in Iraq with the U.S. Marine Corps.

"They sprayed all kinds of stuff on them," Holmes said.

Although the grant money, the first awarded ISM, will fund work in Pullman, he said the organization's supporters hope any subsequent clinical studies will be done in Spokane.

"There's a lot of excitement about making it happen," he said.
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The May 2010 Compensation and Pension bulletin issued by the Veterans' Benefits Administration details new procedures for handling claims based on herbicide exposure in Thailand and Korea.

The complete bulletin is available here for viewing or download.

A summary of the bulletin is posted below.

New Procedures for Claims Based on
Herbicide Exposure in Thailand and Korea



Effective immediately, when regional offices
(ROs) receive disability claims based on exposure to tactical herbicides, such as Agent Orange, from Veterans who served in Thailand or Korea during the Vietnam era, there is no longer a requirement
to send an inquiry to the C&P Service Agent
Orange Mailbox. Development inquiries can be sent directly to the Army and Joint Services Records Research Center (JSRRC) when the available evidence does not indicate tactical herbicide exposure. This will reduce processing time and provide better service to Veterans.

Herbicide related claims from Veterans with
Thailand service

After reviewing documents related to herbicide use in Vietnam and Thailand, C&P Service has determined that there was significant use of herbicides on the fenced in perimeters of military bases in Thailand intended to eliminate vegetation and ground cover for base security purposes.
Evidence of this can be found in a declassified Vietnam era Department of Defense (DoD) document titled Project CHECO Southeast Asia Report: Base Defense in Thailand. Therefore,
when herbicide related claims from Veterans with Thailand service are received, RO personnel should now evaluate the treatment and personnel records to determine whether the Veteran’s
service activities involved duty on or near the perimeter of the military base where the Veteran was stationed.

(FOR FULL DETAILS REFER COMPLETE BULLETIN)