WSU to Study Iraq Toxins' Effect

Spokesman-Review
by Bert Caldwell


Research to examine how exposure might damage offspring of soldiers

Washington State University scientists will use a $1.7 million grant to study what multi-generation genetic damage might be done by toxins U.S. troops could encounter in Iraq.

The research using laboratory rats, not humans, will be the first for the military to examine the epigenetic effects of pesticides, herbicides and other compounds, said lead scientist Michael Skinner, director of the university's Center for Reproductive Biology.

Previous studies have looked at the health effects of other substances, notably the Agent Orange used to defoliate jungles in Vietnam, on the soldiers directly exposed, he said, not on their children or grandchildren.

"The science really had not caught up with the trans-generational stuff," said Skinner, one of several WSU pioneers in the field of epigenetic, or multi-generational, inheritance.

Besides herbicides and pesticides – which and in what combinations has not been determined – the study also will look at the effects of explosives residues, he said.

The four-year study will allow researchers to see how any changes in genetic chemistry that develop are passed along through two subsequent generations of rats, he said, noting that only the first two years of research have been funded.

Among the problems that might develop are kidney disease, or changes in the male and female reproductive organs, he said.

If any genetic markers are identified in rats, Skinner said, follow-up research could look at whether they might show up among members of the military as well.

That would be of particular interest to Dave Holmes, interim chief operating officer of the Institute for Systems Medicine, which was awarded the U.S. Department of Defense grant passed through to Skinner.

Holmes' son, Tim Hammond, did two tours in Iraq with the U.S. Marine Corps.

"They sprayed all kinds of stuff on them," Holmes said.

Although the grant money, the first awarded ISM, will fund work in Pullman, he said the organization's supporters hope any subsequent clinical studies will be done in Spokane.

"There's a lot of excitement about making it happen," he said.
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VA Pressed on High Percentage of Wrongly Denied Benefit Claims
http://www.cqpolitics.com/wmspage.cfm?parm1=1&docID=cqmidday-000003558167
A leading Republican senator on Tuesday asked Veterans Affairs Secretary Eric Shinseki to explain why so many veterans’ benefit claims are wrongly denied, resulting in a high rate of reversal on appeal.

Charles E. Grassley of Iowa, top Republican on the Senate Finance Committee, said that figures cited in a case argued before the Supreme Court last month showed that between 50 percent and 70 percent of veterans’ benefits claims had been unjustifiably denied.


In a letter to Shinseki on Tuesday, Grassley asked what the Department of Veterans Affairs is doing to improve the quality of VA claims decisions and reduce unnecessary appeals.

“The fact that the VA’s decisions are not only overturned on appeal frequently, but that a majority of claims were so wrongly decided in the first place shows me that there are serious, systemic problems with the process for approving veterans’ claims,” Grassley said. “After providing substantial increases in taxpayer dollars to the VA to address the claims backlog, it’s clear that devoting more money alone is not the answer. The VA needs to tackle this problem head on, because without substantial reform, thousands of veterans will continue to face needless delays and red tape.”

Veterans who are wrongly denied benefits often suffer significant harm, Grassley said, even if they eventually prevail. So does the taxpayer, he added, because when the government loses on appeal, it must not only pay the benefits in question, it also must cover the veteran’s attorneys fees when the court finds the government’s position to be unjustified.

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