WSU to Study Iraq Toxins' Effect
Spokesman-Review
by Bert Caldwell
Research to examine how exposure might damage offspring of soldiers
Washington State University scientists will use a $1.7 million grant to study what multi-generation genetic damage might be done by toxins U.S. troops could encounter in Iraq.
The research using laboratory rats, not humans, will be the first for the military to examine the epigenetic effects of pesticides, herbicides and other compounds, said lead scientist Michael Skinner, director of the university's Center for Reproductive Biology.
Previous studies have looked at the health effects of other substances, notably the Agent Orange used to defoliate jungles in Vietnam, on the soldiers directly exposed, he said, not on their children or grandchildren.
"The science really had not caught up with the trans-generational stuff," said Skinner, one of several WSU pioneers in the field of epigenetic, or multi-generational, inheritance.
Besides herbicides and pesticides – which and in what combinations has not been determined – the study also will look at the effects of explosives residues, he said.
The four-year study will allow researchers to see how any changes in genetic chemistry that develop are passed along through two subsequent generations of rats, he said, noting that only the first two years of research have been funded.
Among the problems that might develop are kidney disease, or changes in the male and female reproductive organs, he said.
If any genetic markers are identified in rats, Skinner said, follow-up research could look at whether they might show up among members of the military as well.
That would be of particular interest to Dave Holmes, interim chief operating officer of the Institute for Systems Medicine, which was awarded the U.S. Department of Defense grant passed through to Skinner.
Holmes' son, Tim Hammond, did two tours in Iraq with the U.S. Marine Corps.
"They sprayed all kinds of stuff on them," Holmes said.
Although the grant money, the first awarded ISM, will fund work in Pullman, he said the organization's supporters hope any subsequent clinical studies will be done in Spokane.
"There's a lot of excitement about making it happen," he said.
VA doctors prohibited from prescribing medical pot
ALBUQUERQUE, N.M. (AP) -- When Paul Culkin came home to New Mexico after serving with an Army bomb squad in Iraq, he tried counseling and medications offered by the Department of Veterans Affairs to cope with his post traumatic stress disorder.
Nothing worked very well. Then he found a new alternative: marijuana.
New Mexico is the only state that explicitly allows people with PTSD to smoke pot under its medical marijuana law - an issue that is getting attention around the country at a time when traumatized vets are coming home from wars in Iraq and Afghanistan in large numbers.
New Mexico's medical marijuana law has created a conundrum for the Veterans Affairs, which does not allow its doctors to prescribe pot because the drug is illegal in the eyes of the federal government. So, patients like Culkin must seek out an endorsement from a private doctor.
PTSD accounts for more patients than any other of the state's 16 eligible debilitating conditions approved for medical marijuana treatment.
Culkin wishes the VA could provide it.
"Oh my God, it would be so helpful," said Culkin, 30, who heads the New Mexico Medical Marijuana Patients Group formed last December as a support and education group.
If the VA handled all needs - including medical cannabis - care for veterans would improve, he said, because the doctor would know everything about the patient.
"If these guys fought the hardest they could, why not give them the best medicine, or an alternative medicine you can?" Culkin said.
States where medical marijuana use has been approved have been trying to determine what ailments the drug will help. Those efforts have resulted in a mishmash of regulations.
For instance, a Colorado House committee in March rejected following New Mexico's lead in specifically listing PTSD to qualify for medical marijuana. California doctors can recommend medical marijuana for a variety of conditions and "any other illness for which marijuana provides relief."
The American Medical Association has called for controlled studies of marijuana for patients whose conditions it might help. The association also wants a review of marijuana's status as a Schedule 1 drug so clinical research can move ahead.
The Department of Veterans Affairs says it is developing a national policy, and the head of Veterans for Medical Marijuana Access believes a VA policy allowing medical marijuana "is inevitable."
"We're all on the same side," said Michael Krawitz of Virginia. "My goal is a good outcome for the veteran, and that's their goal."
"The irony in this ... is it's a common thing for veterans to tell me, 'The VA is telling me if I just stay away from medical marijuana, we'll give you all the pills you want, morphine, whatever,'" he said.
Krawitz, 47, was severely injured in a motorcycle accident while stationed in Guam with the Air Force about 20 years ago and eventually received a medical discharge.
He is an advocate for marijuana's medicinal benefits.
"It makes it so you can put down a lot of the pain pills. It helps with nerve pain, that really bad spasming and twitching."
He praises the care he's gotten from the VA, but adds: "I feel sorry for the VA; they're caught in the middle ... They have a clear mandate to take care of veterans."
Given their inability to get medical marijuana from the VA, New Mexico veterans are finding their own go-to physicians, including Dr. Eve Elting in the central part of the state.
"I have guys coming to see me from all over the state, five or six hours' drive, just to be legal," said Elting, of Truth or Consequences. "It's bad enough they have something that makes life so challenging. On top of that they're discriminated against, made to feel like they're doing something wrong."
Elting said veterans hear about her by word of mouth since she will see people who aren't regular patients. About a quarter of those who come to her want medical marijuana for PTSD. One day she saw eight veterans - five for PTSD.
New Mexico doctors do not prescribe medical cannabis. Rather, they certify someone has one of the approved conditions and that standard treatment doesn't work. Patients then apply to the state program. If an application is approved, the patient gets a registry ID card that allows possession of up to 6 ounces of medical marijuana.
A psychiatrist's diagnosis must be included for PTSD. For chronic pain, X-rays or CT scans are required and both a primary doctor and a specialist have to sign off.
"Even though the VA has prohibited them from signing the documents, I don't see why a physician treating the veteran would not be willing to sign a piece of paper attesting that the patient had that condition," said Elting, who did her residency at a VA hospital and serves on New Mexico's eight-member medical advisory board for the program.
Veterans armed with Elting's signature would still have to find a private psychiatrist or other specialist to sign.
"Everyone's happy to give them a million narcotics, anti-psychotics. It's frustrating," she said.