WSU to Study Iraq Toxins' Effect
Spokesman-Review
by Bert Caldwell
Research to examine how exposure might damage offspring of soldiers
Washington State University scientists will use a $1.7 million grant to study what multi-generation genetic damage might be done by toxins U.S. troops could encounter in Iraq.
The research using laboratory rats, not humans, will be the first for the military to examine the epigenetic effects of pesticides, herbicides and other compounds, said lead scientist Michael Skinner, director of the university's Center for Reproductive Biology.
Previous studies have looked at the health effects of other substances, notably the Agent Orange used to defoliate jungles in Vietnam, on the soldiers directly exposed, he said, not on their children or grandchildren.
"The science really had not caught up with the trans-generational stuff," said Skinner, one of several WSU pioneers in the field of epigenetic, or multi-generational, inheritance.
Besides herbicides and pesticides – which and in what combinations has not been determined – the study also will look at the effects of explosives residues, he said.
The four-year study will allow researchers to see how any changes in genetic chemistry that develop are passed along through two subsequent generations of rats, he said, noting that only the first two years of research have been funded.
Among the problems that might develop are kidney disease, or changes in the male and female reproductive organs, he said.
If any genetic markers are identified in rats, Skinner said, follow-up research could look at whether they might show up among members of the military as well.
That would be of particular interest to Dave Holmes, interim chief operating officer of the Institute for Systems Medicine, which was awarded the U.S. Department of Defense grant passed through to Skinner.
Holmes' son, Tim Hammond, did two tours in Iraq with the U.S. Marine Corps.
"They sprayed all kinds of stuff on them," Holmes said.
Although the grant money, the first awarded ISM, will fund work in Pullman, he said the organization's supporters hope any subsequent clinical studies will be done in Spokane.
"There's a lot of excitement about making it happen," he said.




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V.A. secretary: Veterans seeking money must prove service made them sick
By Matthew D. LaPlante
The federal government did not address military members’ exposure to Agent Orange during the Vietnam War “the way that might have been and the way that should have been,” the Secretary of Veterans Affairs said during a brief visit Tuesday to Salt Lake City.
Thousands of Vietnam veterans waited for decades before medical conditions they acquired during the war were connected to exposure to the toxic defoliant. And that meant that many went without the medical care and compensation they deserved while suffering from debilitating diseases caused by their service.
But as evidence mounts suggesting that many of the nation’s latest generation of veterans have been sickened by service in Iraq and Afghanistan, Secretary Eric Shinseki defended a century-old standard requiring scientific proof before veterans can be compensated for their suffering.
Thirty-five years after the end of the Vietnam War, the V.A. is still slowly adding to the list of conditions recognized as related to Agent Orange exposure, including three illnesses — Parkinson’s disease, ischemic heart disease, and B cell leukemias — that have been added to the list under Shinseki’s watch.
The former Army general, himself a combat-wounded veteran of the Vietnam War, said “nothing” was done to immediately respond to veterans who grew inexplicably sick after returning home from Vietnam.
Shinseki said his department was working tirelessly to help veterans establish proof sooner.
“What we’re trying to change is the opportunity to establish the connection,” he said, noting that millions of federal dollars have been poured into research into military members who have been exposed to open-air burn pits — one of the probable culprits in a variety of medical conditions suffered by veterans, including cancer, skin conditions and blood disease.
But in the meantime, the secretary said, the standard requiring medical proof of a disease’s cause is “the law.”
Shinseki was in Utah to meet with veterans officials at the V.A. Regional Medical Center and met briefly with reporters.
He declined to answer a question about whether the law should change for veterans of the current conflicts given the experiences of Vietnam War veterans, many of whom died long before their conditions were acknowledged to have been caused by their service.
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