WSU to Study Iraq Toxins' Effect
Spokesman-Review
by Bert Caldwell
Research to examine how exposure might damage offspring of soldiers
Washington State University scientists will use a $1.7 million grant to study what multi-generation genetic damage might be done by toxins U.S. troops could encounter in Iraq.
The research using laboratory rats, not humans, will be the first for the military to examine the epigenetic effects of pesticides, herbicides and other compounds, said lead scientist Michael Skinner, director of the university's Center for Reproductive Biology.
Previous studies have looked at the health effects of other substances, notably the Agent Orange used to defoliate jungles in Vietnam, on the soldiers directly exposed, he said, not on their children or grandchildren.
"The science really had not caught up with the trans-generational stuff," said Skinner, one of several WSU pioneers in the field of epigenetic, or multi-generational, inheritance.
Besides herbicides and pesticides – which and in what combinations has not been determined – the study also will look at the effects of explosives residues, he said.
The four-year study will allow researchers to see how any changes in genetic chemistry that develop are passed along through two subsequent generations of rats, he said, noting that only the first two years of research have been funded.
Among the problems that might develop are kidney disease, or changes in the male and female reproductive organs, he said.
If any genetic markers are identified in rats, Skinner said, follow-up research could look at whether they might show up among members of the military as well.
That would be of particular interest to Dave Holmes, interim chief operating officer of the Institute for Systems Medicine, which was awarded the U.S. Department of Defense grant passed through to Skinner.
Holmes' son, Tim Hammond, did two tours in Iraq with the U.S. Marine Corps.
"They sprayed all kinds of stuff on them," Holmes said.
Although the grant money, the first awarded ISM, will fund work in Pullman, he said the organization's supporters hope any subsequent clinical studies will be done in Spokane.
"There's a lot of excitement about making it happen," he said.





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VA tests system for electronic disability claims
By KIMBERLY HEFLING
Associated Press Writer
VA seeks to make getting benefits easier for vets
BALTIMORE (AP) -- If the interminable backlog of veterans' disability claims has any chance of being eliminated, the system must go paperless.
But how to move to a fully electronic system is the quandary, and one Veterans Affairs Secretary Eric Shinseki wants resolved by 2012, when a modern system is to start rolling out.
At a Baltimore VA office, which Shinseki visited Wednesday, 30 claims processors have been rotated in to meticulously review virtual test pages. They are part of the conversation as VA officials address difficult questions: Should millions of veterans' files in storage be scanned? How is a veteran's privacy going to be protected? What questions should veterans be asked as they fill out an automated form to start the claims process?
"This is about turning a chapter in VA history," Shinseki said. "It's a serious, huge undertaking."
Without a system overhaul, the VA estimates that by 2015, that backlog of disability claims will increase tenfold to about 2.6 million. Those with service-connected injuries already wait an average of about five months to have a claim processed, and there are frequent complaints about lost paperwork and inaccuracy.
Under the current system, people in only one location at a time can look at a veteran's claim, which requires that boxes of paperwork be shipped across the United States. Under the new system, the goal is an electronic file that people in several locations can view simultaneously.
Robert Graham, a claims processor who works for the VA in Winston-Salem, N.C., and was brought in for the review, said it typically takes him six to 12 hours to do his part in processing claims from Iraq and Afghanistan veterans. That time would be cut 70 percent under a new system, he said.
Baltimore is one of four pilot sites. The others are in Providence, R.I., Little Rock, Ark., and Pittsburgh.
The complexity and volume of cases from veterans of the current conflicts have added to the backlog. It's expected to grow primarily because Shinseki in October made it easier for potentially 200,000 sick Vietnam veterans who were exposed to the Agent Orange herbicide to receive service-connected compensation. Under his watch, the VA has also said it will take a second look at the rejected claims of sick Gulf War veterans.
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